KlariFi™ Software
KlariFi™ is an intuitive, end-to-end recipe-driven automation software for downstream bioprocessing professionals using Repligen systems for filtration or chromatography.
END-TO-END AUTOMATION
Powered by six application modules for GMP compliant automated control throughout the entire process.
ENHANCED PROCESS CONTROL
Visualize process data, pause and adjust during a run without compromising batch integrity.
EXTENSIVE RECIPE LIBRARY
Preloaded with a series of fully configurable template recipes for common process steps within your unit operation.
Discover the Recipe Editor
Your process is only as good as your recipe. Developed by bioprocessing experts to be fully customizable with version controls and approval routing, the KlariFi™ recipe editor unlocks the full potential of every run. Leverage the extensive library of pre-built templates to fast-track production or enjoy the flexibility of building recipes from the ground up. Visualize process flow with ease using sequential flow charts and adjust during a run without compromising batch integrity.
- Absolute control: From individual components to structuring runs based on defined calculations to adapting process using in-line concentration data. Users are no longer handicapped by limitations inherent in other software platforms. With KlariFi™ operators have absolute control over process.
One Software Platform for Downstream Bioprocessing
Depending on the processes within a workflow, operators may have to toggle between many different software platforms and devices, creating confusion and additional learning curves. The KlariFi™ software brings clarity to the process with one platform for all of downstream. Use KlariFi™ to run purification steps on the Repligen KRM™ Chromatography system as well as ultrafiltration/diafiltration across many KrosFlo® TFF systems. Operator benefits include:
- Streamlined processes: different unit operations, same automation platform
- Simplified training: Onboarding, resources, and time spent training users are minimized
- Standardized data: Consistent and compliant data storage, formatting, and transfer for easy analysis
Detailed Reporting at Your Fingertips
Monitored, auto-generated and securely stored in a SQL database, KlariFi™ puts operators in control of all their process data.
- In-depth analysis: Evaluate historical or live data with +1,000 tag values available
- Process visualization: Sequential flow charts and custom trending options enable review of process flow with ease
- Robust recordkeeping: All electronic batch, alarm, and event data captured in keeping with GMP standards
- DCS/SCADA connectivity
- OPC/OPCUA Ethernet IP
- Interlocks
- Filter Selection
- Totalizers
- PID Selection
- Mixer Speed
- Pump Mode
- PCV Mode
- Batch Creation
- Recipe Execution
- Prompts
- Parameters
- 21 CFR Part 11
- GAMP 5 - Category 4
- ISA-88 Standards
- ALCOA+
- KrosFlo RS TFF systems
- KrosFlo KTF+ TFF systems
- KRM Chromatography systems
Related Products
KrosFlo® RS TFF Systems
The KrosFlo® RS are a series of tangential flow filtration (TFF) systems engineered for an era of new modalities. These systems are single-use and cGMP compliant with features like end-to-end automation, minimal hold-up volumes, and effortless scalability. Support automated ultrafiltration and diafiltration (UF/DF) processes for batch volume ranges of 35mL to 2000L.
