Bioprocessing Solutions that Accelerate Process Development and Manufacturing

From mAbs and ADCs to mRNA, cell and gene therapy, Repligen helps teams improve yield, reduce risk, and scale with confidence.

Solutions by Modality

Start with your modality. Build the right process.

Each modality requires a different process strategy. We help you align the right technologies to improve yield, protect product quality, and scale with fewer surprises.

3D molecular visualization of a monoclonal antibody (mAb) structure used in biologics development and therapeutic manufacturing.

Monoclonal Antibodies

Increase productivity, optimize purification, and scale with confidence.

Read More
3D molecular visualization of an antibody‑drug conjugate (ADC) structure used in advanced biologics and targeted therapeutic development.

ADCs

Improve control and reduce risk in complex workflows.

Read More
3D molecular visualization of messenger RNA (mRNA) structure used in gene therapy, vaccines, and advanced biologics development.

mRNA

Enable fast, flexible manufacturing and scale-up.

Read More
3D molecular visualization of circular plasmid DNA structure used in gene therapy, cell therapy, and advanced biomanufacturing workflows.

pDNA

Support robust plasmid production with filtration, chromatography, PAT, and fluid management solutions.

Read More
3D molecular visualization of an adeno‑associated virus (AAV) vector used for gene therapy and viral vector delivery applications.

Viral Vectors

Improve productivity and scale viral vector processes.

Read More

Why teams choose Repligen

Repligen focuses on the steps that matter most where better process control, reproducibility, and productivity directly impact timelines, cost, and supply.

Our solutions span process intensification, TFF, chromatography, process analytics, and single-use fluid management across upstream and downstream workflows.

Higher Productivity
Produce more drug in less time.

Process Robustness
Reduce variability at critical steps.

Faster Timelines
Move from development to GMP with fewer delays.

Modality Flexibility
Support today's pipeline and what comes next.

Built for Every Decision-Maker

What each team needs to move forward

  • Process Development Scientists

    Accelerate optimization and improve process understanding earlier.

  • MSAT Engineers

    Reduce transfer risk and scale with consistency.

  • Procurement & Operations

    Simplify deployment and improve supply reliability.

  • Leadership

    Increase yield, reduce cost, and shorten timelines.

Scientists analyzing cell culture images and experimental data at a laboratory workstation with microscopes and digital imaging systems.
Products

Core technologies. Clear outcomes.

Each platform is designed to improve yield, speed, and control across modalities and at every scale.

Repligen XCell ATF single‑use perfusion system with controller and hollow fiber module used for intensified cell culture processes.

Upstream Filtration

Increase productivity with perfusion and ATF technologies designed to improve space-time yield.

Read More
Repligen KrosFlo RS 10 tangential flow filtration (TFF) system with automated control console and scale for bioprocessing.

Downstream Filtration

Optimize UF/DF with TFF solutions engineered for efficient processing and strong product recovery.

Read More
Chromatography System featuring a stainless steel industrial design, integrated touchscreen interface, and OPUS 25 pre-packed chromatography column for automated downstream bioprocessing

Chromatography

Streamline purification with pre-packed columns and scalable systems.

Read More
Repligen PATsmart product family featuring ZipChip, MAVEN, REBEL XT, FlowVPX, and SoloVPE Plus analytical instruments for bioprocessing and PAT applications

Process Analytics / PAT

Monitor critical parameters in real time to reduce risk.

Read More
Repligen ProConnex MixOne RG-X single-use mixing system featuring Metenova Zero Gravity technology and RG-V film for sterile, low-shear bioprocessing and vaccine manufacturing.

Single-Use Fluid Management

Simplify fluid handling with scalable, ready-to-use systems.

Read More

Increase productivity without increasing footprint

Repligen’s process intensification approach combines perfusion, TFF, process analytics, and single-use systems to help you achieve higher cell densities, better product quality, and improved space-time yield without expanding facilities.

 Repligen XCell ATF System family including Lab and LS controllers with single-use and stainless steel devices for upstream process intensification.

Trusted across biopharmaceutical manufacturing

  • Supporting the world’s leading biopharma and CDMO companies
  • Deployed in process development and GMP facilities
  • Proven in clinical and commercial processes
  • Award winning innovations and technologies
Our solutions are used in yield-critical and time-critical steps where better control and reproducibility directly impact performance.
Looking Ahead

Building more connected, controllable processes

Bioprocessing is moving toward continuous manufacturing and real-time control. Repligen helps teams get there with integrated analytics, UF/DF optimization, and technologies that enable more predictable, data-driven processes:

  • Products Designed for Continuous Processing
  • Real-Time Analytics
  • Automation & Integration Solutions
  • AI-Enabled Tools for Optimization
  • Solutions Enabling Flexible Manufacturing

Learn More

Build the right process. Scale with confidence.

Whether you are developing mAbs, scaling mRNA, or advancing cell and gene therapies, Repligen helps you design processes that are more productive, more reproducible, and ready for scale.