KrosFlo® TFF Systems
Turnkey systems for tangential flow filtration (TFF), KrosFlo® Systems are compatible with single-use hollow fiber filters and/or flat sheet cassettes, modernizing how UF/DF is performed at every stage from process development to large-scale manufacturing.
Discover your next KrosFlo® TFF System
Adored and economical with good automation 5mL - 500L
Revered for its simplicity and capability, the Repligen KrosFlo® KR2i, KMPi, and FS family of systems are some of the most widely used lab scale TFF platforms in the world.
KrosFlo® KR2i TFF System
Single-use fully integrated benchtop TFF system for research and process development (PD) ranging from 2mL - 15L. Compatible with hollow fiber and flat sheet filters, this system features a peristaltic feed pump with 13 automated process modes.
Powered by Bioz
KrosFlo® KMPi TFF System
Fully automate 100 ml - 500 L UF/DF processes using an unparalleled combination of hardware integration with peristaltic pump, configurability and automation through modular, plug-and-play hardware.
Highly configurable, small footprint with better automation 200L - 5000L
Popular in pilot scale and flexible manufacturing environments, the KrosFlo® KTF series offers unrivalled configurability to support multiple scales, unit operations and solutions while retaining a small footprint. Customization available upon request.
KrosFlo® KTF TFF Systems
The KrosFlo KTF are a series of highly configurable single-use TFF systems for multiple unit operations, applications, and filter types. With volumes spanning across 1 to 5000L, users enjoy the unrivaled flexibility of processing large and small batch sizes within the same platform.
cGMP compliant with end-to-end automation 35mL - 2000L
Ideal for mRNA and gene therapy production, KrosFlo® RS TFF series are industrial grade, fully automated cGMP manufacturing systems designed to take on an era of new modalities. Customization available upon request.
KrosFlo® RS TFF Systems
The KrosFlo® RS are a series of tangential flow filtration (TFF) systems engineered for an era of new modalities. These systems are single-use and cGMP compliant with features like end-to-end automation, minimal hold-up volumes, and effortless scalability. Support automated ultrafiltration and diafiltration (UF/DF) processes for batch volume ranges of 35mL to 2000L.
PAT-Driven Control with Real-Time Concentration Analytics
Introducing our groundbreaking Real-time Process Management (RPM™) line of TFF instruments, a cutting-edge solution designed to revolutionize process control in tangential flow filtration (TFF) systems. At the core of this innovation lies the integration of the CTech™ FlowVPX® in-line UV-Vis spectrophotometer into our KrosFlo® TFF Systems, providing users with unprecedented real-time insights and control over ultrafiltration/diafiltration (UF/DF) processes during downstream bioprocess development.
Real-time Process Management Solutions
Our Real-time Process Management (RPM™) Systems establish a new benchmark for real-time process control in downstream bioprocessing by integrating of the CTech™ FlowVPX® in-line UV-Vis spectrophotometer into the KrosFlo® TFF Systems. This innovative solution empowers users to achieve unparalleled control and optimization of UF/DF processes, driving efficiency, quality, and innovation in biomanufacturing.