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Solutions

ADVANCING BIOPROCESSING

With a culture of innovation, and focused on cost and process efficiencies, Repligen specializes in applications of technologies and solutions that help set new standards in perfusion, process intensification, enhanced vector titer and recovery yield, continuous manufacturing, and more.

By modality By unit operation By product

Process Intensification

MORE. FASTER.

Bioprocess intensification is defined as a significant step increase in output relative to cell concentration, time, reactor volume or cost, resulting in improvements in productivity, environmental and economic metrics.

Ultrafiltration | Diafiltration

Used in nearly every bioprocessing workflow, ultrafiltration/diafiltration (UF/DF) is a critical purification process, using tangential flow filtration (TFF), prior to final drug formulation.

Continuous Manufacturing

FROM BATCH TO CONTINUOUS

Continuous manufacturing is a method for manufacturing pharmaceutical products from end-to-end on a single, uninterrupted production line. The aim is to eliminate batch inefficiencies that result in process stoppages, long hold times, and sub-optimal facility utilization.

Real-time Process Management Solutions

Our Real-time Process Management (RPM™) Systems establish a new benchmark for real-time process control in downstream bioprocessing by integrating of the CTech™ FlowVPX® in-line UV-Vis spectrophotometer into the KrosFlo® TFF Systems. This innovative solution empowers users to achieve unparalleled control and optimization of UF/DF processes, driving efficiency, quality, and innovation in biomanufacturing.

Process Analytics

Our process analytics solutions, featuring Variable Pathlength Spectroscopy for at-line and in-line concentration monitoring systems, ensure that products meet required Process Analytical Technology (PAT) standards. These tools provide critical data for optimizing bioprocesses and ensuring compliance with regulatory requirements. 

ATMP

Advanced Therapy Medical Products (ATMP) have immense potential to transform the lives of patients with genetic diseases. Repligen partners with developers and manufacturers, providing technology breakthroughs and high impact solutions for plasmid and viral vector development and manufacturing.

Fluid Management

Repligen offers innovative, designed-for-purpose storage and transfer solutions for fluid management within and between unit operations. These include flow paths, tubing, valves and gaskets, bottles and containers, totes, carts and cleanroom process equipment.