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Impact of Single-use Tangential Flow Filtration on Downstream Bioprocessing
Learn how SIUS™ Single-use Flat Sheet Cassettes can impact downstream productivity and process economics. May 7, 2017 | 20 minutes
Knowledge Base
• Data Sheets • Webinars • Seminars • Videos • The R Factor • Scientific Posters • Publications • 3rd Party Articles
Data Management for ViPER ANLYTX
Configurability and Compliance for Automated TFF up to 500L
Driven by the rise in cell and gene therapies, TFF unit operations at scales from 10 mL to 500 L now require the single-use, automation and data integrity capabilities previously reserved for larger scale systems. The newly developed KrosFlo® KMPi TFF System from Repligen provides walk-away automation for concentration, diafiltration and fed-batch processes with TMP control, closed and single-use flow paths and 21 CFR Part 11 software compliance for processes up to 500L. Key components to this new system include: a patented automatic back-pressure control valve, a proprietary control board that enables plug-and-play hardware connectivity and modern software built upon a secure SQL database. Key technical features and applications supported by flexible configurations of the KrosFlo® KMPi TFF System will be discussed.
TangenX Membranes – Repligen
ProStream and HyStream, two modified Polyethersulfone (mPES) membrane chemistries, are used in TangenX® flat sheet cassettes, offering superior selectivity for a wide range of applications. ProStream membrane is neutrally charged, rendering it low binding for enhanced flux and recovery HyStream membrane is extremely hy
DOC0242 ConfiRM Slope Reference Materials Specification Sheet
Introducing NaOH-stable AAV affinity resins: the first chapter of a growing catalog
The first and only NaOH-cleanable affinity resins for AAV2, AAV8 and AAV9 have been developed using a breakthrough development platform based on unprecedented ligand diversity. Performance metrics for capacity, yield and purity meet or exceed existing AAV resins while also withstanding more than 20 CIP cycles with 0.5 M NaOH. Off-the-shelf resin availability pre-packed in OPUS® Columns, as well as loose resin, enables streamlined implementation. The technical basis of the development platform and example data will be discussed.
Spectra/Por 3 Dialysis Membranes – Repligen
Spectra/Por 3 Dialysis Membrane Dry with or without glycerin 3.5 kD MWCO Rolled tubing, Trial Kits, Ready-To-Use Sacks, Flat sheets
Spectra/Por 4 Dialysis Membranes – Repligen
Spectra/Por 4 Dialysis Membrane Dry tubing with glycerin 12-14 kD MWCO Rolled tubing, Trial Kits, Ready-To-Use Sacks, Flat sheets
DOC0207 CTech FlowVPX 10 mm Flow Cell Specification Sheet
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