SpectraPor® Biotech Grade Cellulose Ester (CE) Dialysis Membrane
Repligen produces molecular porous Biotech Grade Cellulose Ester (CE) membranes in a large range of MWCO’s specifically for critical MW separations using a proprietary casting process free of heavy metal and sulfur contaminants. The CE dialysis tubing is ultra-pure and does not require special cleaning or treatment.
Biotech Cellulose Ester (CE) dialysis tubing and kits
Biologically inert and ultra-pure, SpectraPor® Biotech CE Dialysis Membrane provides superior molecular selectivity and is available in the largest selection of 9 concise MWCO's ranging from 0.1 – 1,000 kD, whether purifying small MW solutes or isolating large macromolecules or nanoparticles. Biotech CE membrane generally tolerates weak or dilute acids & bases and mild alcohols and is compatible with pH 2-9 and temp 4-37 °C. Exposure to most organic solvents is not recommended and should be confirmed on the Repligen Chemical Compatibility table.
Simply soak and rinse in DI water, apply Universal Tubing Closures and load sample.
Features and benefits
- High purity for critical and GMP dialysis - no heavy metals or sulfides
- Rigidly controlled porosity for better selectivity & separations
- No interference with macromolecular activity & function
- No glycerin removal and no pretreatment required
- Available in rolled tubing for economy and trial kits for evaluation
Typical Dialysis Applications for Biotech CE
- Salt removal and HPLC sample preparation
- pH change, buffer exchange and final formulation
- Purification of Protein, DNA, plasmids, macromolecules, nanoparticles and liposomes
- Polymer synthesis and isolation (polypeptide, oligonucleotide, polysaccharide)
- Biopolymer and hydrogel purification (hyaluronic acid, collagen, chitosan)
- Large volume and GMP batch process dialysis
- Enzyme activity and ligand binding studies
- Drug dissolution and controlled release studies
- DNA and Protein electroelution
Product specifications
| Properties: | Mildly hydrophobic, symmetric porosity |
| 9 MWCO's: | 0.1-0.5 kD, 0.5-1.0 kD, 3.5-5 kD, 8-10 kD, 20 kD, 50 kD, 100 kD, 300 kD, 1000 kD |
| 4 Flat Widths: | 10 mm, 16 mm, 24 mm, 31 mm |
| Quantity & Packaging: | Wet in 0.05% sodium azide, 10 m/roll or 1 m/trial kit (includes 2 closures) |
|
MWCO (kD) |
Flat Width (mm) |
Diameter (mm) |
Vol/Length (ml/cm) |
Part No. |
|
0.1 - 0.5 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
0.5 - 1.0 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
3.5 - 5 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
8 - 10 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
20 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
50 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
100 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
300 |
16 31 |
10 20 |
0.79 3.1 |
|
|
1000 |
16 31 |
10 20 |
0.79 3.1 |
|
MWCO (kD) |
Flat Width (mm) |
Diameter (mm) |
Vol/Length (ml/cm) |
Part No. |
|
0.1 - 0.5 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
0.5 - 1.0 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
3.5 - 5 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
8 - 10 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
20 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
50 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
100 |
10 16 24 31 |
6.4 10 15 20 |
0.32 0.79 1.8 3.1 |
|
|
300 |
16 31 |
10 20 |
0.79 3.1 |
|
|
1000 |
16 31 |
10 20 |
0.79 3.1 |
