Tulip tank case study: The unrecognized role of mixing during TFF

Tulip tank case study: The unrecognized role of mixing during TFF

The degree of homogeneity in the feed that is delivered to the filters is a critical but often overlooked factor. Even small changes in the nature of the feed will drastically impact performance, resulting in deviations during diafiltration.

This case study explores the impact of mixing dynamics on TFF performance. An innovative single-use Tulip Tank paired with the KrosFlo® RS 30 TFF system significantly improved performance as compared to traditional retentate vessels, reducing the gap between theoretical models and actual outcome.